- Do not take Nurofen Plus Tablets if you: are allergic to ibuprofen, codeine, or any of the ingredients of Nurofen Plus.
- Have experienced shortness of breath, worsening of asthma, allergic rash or an itchy, runny nose when taking ibuprofen, codeine, aspirin or other similar medicines.
- Are already taking non steroidal anti-inflammatory drugs
- Have ever had stomach bleeding or perforation after taking ibuprofen, aspirin or other similare medicines
- have or have ever had a stomach ulcer, perforation or bleeding
- Having breathing difficulties
- Suffer from severe kidney, liver or heart problems
- Suffer from chronic constipation
- Are under 12 years of age
- For pain relief in children and adolescents (0-18 years of age) after removal of their tonsils or adenoids due to obstructive sleep apnoea syndrome
- You know that you metabolise very rapidly codeine into morphine
- Are in the last trimester of pregnancy or breast feeding see pregnancy and breastfeeding)
- Are already taking monoamine oxidase inhibitors (MAOIs)
Consult your doctor or Pharmacist before taking Nurofen Plus tablets if you:
- Have asthma or have suffered from asthma
- Have kidney, liver or heart problems
- Have heart problems including heart failure, angina, or if you have had a heart attack, bypass surgery, peripheral artery disease (poor circulation in the legs or feet due to narrow or blocked arteries), or any kind of stroke (including “mini-stroke” or transient ischaemic attack “TIA”)
- Have stomach or intestinal problems (such as Crohn’s desease or ulcerative colitis)
- Have low or high blood pressure)
- Have a head injury or raised intracranial pressure
- suffer from a thyroid disorder
- suffer from a connective tissue disease such as Systemic Lupus Erythematosus (SLE) (Lupus)
- Are elderly
- Are receiving regular treatment from your doctor
- Have an adrenal gland deficiency
- Have a bowel obstruction
- Are taking other codeine medicines
- Have a congenital or acquired muscle weakness
- Have a history of confulsions or drug abuse
- Have chicken pox (varicella), as it is advisable to avoid the use of Nurofen Plus tablets.
Children and adolescents older than 12 years of age: There is a risk of renal impairment in dehydrated children and adolescents.
Use in children and adolescents after surgery: Codeine should not be used for pain relief in children and adolescents after removal of their tonsils or adenoids dur to Obstructive Sleep Apnoea Syndrome.
Use in children with breathing problems:
Codeine is not recommended in children with breathing problems, since the symptoms of morphine toxicity may be worse in these children.
Nurofen Plus is not recommended in adolescents with compromised respiratory function for the treatment of cough and or cold.
Please tell your doctor of pharmacist if you are taking or have recently taking other medicines.