Adults over the age of 18: Apply one new patch (of appropriate strength) to the skin when you wake up (usually in the morning). Remove 16 hours later which is usually at bed time.Apply one new 15mg Invisi Patch to the skin when you wake. Do this for the first 8 weeks. Then apply one new 10mg Invisi Patch to the skin when you wake. Do this for the next 4 weeks.The active ingredient is nicotine.